Can lupus nephritis lead to kidney failure?
Yes, if untreated or poorly controlled. With modern immunosuppressive therapy, many patients achieve remission and preserve kidney function.
Treatment
Lupus nephritis
How systemic lupus erythematosus affects the kidneys and treatment approaches in India.
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Short Answer
Lupus nephritis occurs when the immune system attacks the kidneys as part of systemic lupus erythematosus (SLE), requiring immunosuppressive treatment to prevent kidney failure.
Medical Facts
- Up to 50% of SLE patients develop some degree of kidney involvement during their disease course.
- Kidney biopsy is essential to classify the type (Class I-VI) and guide treatment intensity.
- Treatment typically involves high-dose steroids combined with cyclophosphamide or mycophenolate mofetil.
Treatment or Donation Options
- Get regular urine and blood tests to monitor for kidney involvement if you have lupus.
- Discuss kidney biopsy with your rheumatologist or nephrologist if proteinuria or declining GFR is detected.
- Understand your lupus nephritis class and what it means for treatment duration and prognosis.
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